Mus musculus Protein: Adnp
Summary
InnateDB Protein IDBP-213112.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adnp
Protein Name activity-dependent neuroprotective protein
Synonyms AA589558; mKIAA0784;
Species Mus musculus
Ensembl Protein ENSMUSP00000085316
InnateDB Gene IDBG-213108 (Adnp)
Protein Structure
UniProt Annotation
Function Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity Expressed in the brain, with a higher expression in cerebellum and hippocampus. Weakly expressed in lung, kidney and intestine, and expressed at intermediate level in testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0043524 negative regulation of neuron apoptotic process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1338758
InterPro IPR001356 Homeobox domain
IPR007087 Zinc finger, C2H2
IPR009057 Homeodomain-like
IPR015880 Zinc finger, C2H2-like
PFAM PF00046
PF00096
PRINTS
PIRSF
SMART SM00389
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z103
PhosphoSite PhosphoSite-Q9Z103
TrEMBL Q8BNY2
UniProt Splice Variant
Entrez Gene 11538
UniGene Mm.201322
RefSeq NP_033758
MGI ID
MGI Symbol Adnp
OMIM
CCDS CCDS38342
HPRD
IMGT
EMBL AF068198 AK079160 AK129214 BC050833 BC090840 BX005039
GenPept AAD19843 AAH50833 AAH90840 BAC37563 BAC98024