InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Smarcd2

Summary

InnateDB Protein

IDBP-213365.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Smarcd2

Protein Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

Synonyms

AW322457; Baf60b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021052

InnateDB Gene

IDBG-267922 (Smarcd2)

Protein Structure

UniProt Annotation

Function

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0005515	protein binding
GO:0031492	nucleosomal DNA binding

Biological Process

GO:0006337	nucleosome disassembly
GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0043044	ATP-dependent chromatin remodeling