Version 5.4
Mus musculus Protein: Amz2
Summary
InnateDB Protein IDBP-213807.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Amz2
Protein Name archaelysin family metallopeptidase 2
Synonyms AA408420; ESTM12; X83328;
Species Mus musculus
Ensembl Protein ENSMUSP00000090157
InnateDB Gene IDBG-213805 (Amz2)
Protein Structure
UniProt Annotation
Function Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze neurogranin nor angiotensin-2 (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Predominantly expressed in testis. {ECO:0000269PubMed:17074343}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:104837
InterPro IPR012962 Peptidase M54, archaemetzincin
PFAM PF07998
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q400C8
PhosphoSite PhosphoSite-Q400C8
TrEMBL B1AT59
UniProt Splice Variant
Entrez Gene 13929
UniGene Mm.408193
RefSeq NP_079551
MGI ID
MGI Symbol Amz2
OMIM
CCDS CCDS25579
HPRD
IMGT
EMBL AJ879914 AK004062 AK075748 AK077195 AL645791 BC025087
GenPept AAH25087 BAB23148 BAC35928 BAC36674 CAI53759

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca