Version 5.4
Mus musculus Protein: Abca6
Summary
InnateDB Protein IDBP-213930.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abca6
Protein Name ATP-binding cassette, sub-family A (ABC1), member 6
Synonyms 6330565N06Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000035458
InnateDB Gene IDBG-213928 (Abca6)
Protein Structure
UniProt Annotation
Function Probable transporter which may play a role in macrophage lipid homeostasis. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed with higher expression in heart, lung, brain, spleen and testis. {ECO:0000269PubMed:12532264}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1923434
InterPro IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00005
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K441
PhosphoSite PhosphoSite-Q8K441
TrEMBL
UniProt Splice Variant
Entrez Gene 76184
UniGene Mm.159704
RefSeq NP_671751
MGI ID
MGI Symbol Abca6
OMIM
CCDS CCDS25590
HPRD
IMGT
EMBL AF498361 AK040652 AK042934 AK053384 AL603792 BC132417 BC132419
GenPept AAI32418 AAI32420 AAM90907 BAC30657 BAC31409 BAC35372 CAM20973

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca