Version 5.4
Mus musculus Protein: Tmc8
Summary
InnateDB Protein IDBP-214580.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmc8
Protein Name transmembrane channel-like gene family 8
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000051878
InnateDB Gene IDBG-214578 (Tmc8)
Protein Structure
UniProt Annotation
Function Probable ion channel. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in thymus, lung, prostate, placenta, testis and spleen. {ECO:0000269PubMed:12812529, ECO:0000269PubMed:12906855}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006811 ion transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2669037
InterPro IPR012496 TMC
PFAM PF07810
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TN58
PhosphoSite PhosphoSite-Q7TN58
TrEMBL B1ATC0
UniProt Splice Variant
Entrez Gene 217356
UniGene Mm.488728
RefSeq NP_862904
MGI ID
MGI Symbol Tmc8
OMIM
CCDS CCDS25689
HPRD
IMGT
EMBL AK136329 AK171772 AL645856 AY236501 AY263160 BC138254
GenPept AAI38255 AAP69879 AAP78775 BAE22935 BAE42658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca