Version 5.4
Mus musculus Protein: C1qtnf1
Summary
InnateDB Protein IDBP-214648.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C1qtnf1
Protein Name C1q and tumor necrosis factor related protein 1
Synonyms 1600017K21Rik; CTRP1; Zsig37;
Species Mus musculus
Ensembl Protein ENSMUSP00000017590
InnateDB Gene IDBG-214646 (C1qtnf1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005518 collagen binding
Biological Process
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0010544 negative regulation of platelet activation
GO:0010628 positive regulation of gene expression
GO:0010906 regulation of glucose metabolic process
GO:0043410 positive regulation of MAPK cascade
GO:0051260 protein homooligomerization
GO:0051897 positive regulation of protein kinase B signaling
GO:0070208 protein heterotrimerization
GO:0090331 negative regulation of platelet aggregation
GO:2000860 positive regulation of aldosterone secretion
Cellular Component
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID MGI:1919254
InterPro IPR001073 Complement C1q protein
IPR008160 Collagen triple helix repeat
IPR008983 Tumour necrosis factor-like domain
PFAM PF00386
PF01391
PRINTS PR00007
PIRSF
SMART SM00110
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QXP7
PhosphoSite PhosphoSite-Q9QXP7
TrEMBL Q8R1P2
UniProt Splice Variant
Entrez Gene 56745
UniGene Mm.488186
RefSeq NP_001191059
MGI ID
MGI Symbol C1qtnf1
OMIM
CCDS CCDS25703
HPRD
IMGT
EMBL AF192499 AK005484 AK145104 AL591075 BC023468 BC049894 DQ002394
GenPept AAF06664 AAH23468 AAH49894 AAY21926 BAB24070 BAE26237 CAM15757

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca