Version 5.4
Mus musculus Protein: 2310003H01Rik
Summary
InnateDB Protein IDBP-214790.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol 2310003H01Rik
Protein Name RIKEN cDNA 2310003H01 gene
Synonyms Faap100;
Species Mus musculus
Ensembl Protein ENSMUSP00000026448
InnateDB Gene IDBG-214788 (2310003H01Rik)
Protein Structure
UniProt Annotation
Function Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0003810 protein-glutamine gamma-glutamyltransferase activity
GO:0005515 protein binding
Biological Process
GO:0006281 DNA repair
GO:0008150 biological_process
GO:0018149 peptide cross-linking
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043240 Fanconi anaemia nuclear complex
GO:0045111 intermediate filament cytoskeleton
Protein Structure and Domains
PDB ID MGI:1919135
InterPro IPR008958 Transglutaminase, C-terminal
IPR011044 Quinoprotein amine dehydrogenase, beta chain-like
PFAM PF00927
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2ACJ2
PhosphoSite PhosphoSite-A2ACJ2
TrEMBL
UniProt Splice Variant
Entrez Gene 71885
UniGene Mm.488542
RefSeq NP_082256
MGI ID
MGI Symbol 2310003H01Rik
OMIM
CCDS CCDS49004
HPRD
IMGT
EMBL AK148234 AL669855 BC034203 BC048376
GenPept AAH34203 AAH48376 CAM27039

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca