Version 5.4
Mus musculus Protein: Ptchd3
Summary
InnateDB Protein IDBP-215014.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptchd3
Protein Name patched domain containing 3
Synonyms 4930451E13Rik; 4933440L20Rik; RNDEu-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000035709
InnateDB Gene IDBG-215012 (Ptchd3)
Protein Structure
UniProt Annotation
Function May play a role in sperm development or sperm function. {ECO:0000269PubMed:17904097}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes to the midpiece of the sperm tail. {ECO:0000269PubMed:17904097}.
Disease Associations
Tissue Specificity Expressed in germ cells of the testis (at protein level). {ECO:0000269PubMed:17904097}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008158 hedgehog receptor activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0097225 sperm midpiece
Protein Structure and Domains
PDB ID MGI:1921925
InterPro IPR000731 Sterol-sensing domain
IPR003392 Patched
PFAM PF02460
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q0EEE2
PhosphoSite PhosphoSite-Q0EEE2
TrEMBL
UniProt Splice Variant
Entrez Gene 74675
UniGene Mm.61213
RefSeq NP_083325
MGI ID
MGI Symbol Ptchd3
OMIM
CCDS CCDS49014
HPRD
IMGT
EMBL AB235902 AK015440 AK017136 AL663041
GenPept BAB29848 BAB30614 BAF32146 CAM21595

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca