InnateDB Protein
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IDBP-21644.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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UGT2A3
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Protein Name
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UDP glucuronosyltransferase 2 family, polypeptide A3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000251566
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InnateDB Gene
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IDBG-21642 (UGT2A3)
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Protein Structure
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Function |
UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
0
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Protein-DNA |
3
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0015020
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glucuronosyltransferase activity
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GO:0016758
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transferase activity, transferring hexosyl groups
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GO:0030246
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carbohydrate binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002213
UDP-glucuronosyl/UDP-glucosyltransferase
IPR007235
Glycosyl transferase, family 28, C-terminal
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PFAM |
PF00201
PF04101
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6UWM9
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PhosphoSite |
PhosphoSite-Q6UWM9
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TrEMBL |
F5GY78
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UniProt Splice Variant |
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Entrez Gene |
79799
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UniGene |
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RefSeq |
NP_079019
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HUGO |
HGNC:28528
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OMIM |
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CCDS |
CCDS3525
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HPRD |
08646
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IMGT |
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EMBL |
AC021146
AK025587
AY358727
AY542891
BC130533
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GenPept |
AAI30534
AAQ89089
AAS48425
BAB15179
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