Version 5.4
Homo sapiens Protein: CSN1S1
Summary
InnateDB Protein IDBP-22005.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSN1S1
Protein Name casein alpha s1
Synonyms CASA; CSN1;
Species Homo sapiens
Ensembl Protein ENSP00000246891
InnateDB Gene IDBG-22003 (CSN1S1)
Protein Structure
UniProt Annotation
Function Important role in the capacity of milk to transport calcium phosphate.Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1 receptors.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Mammary gland specific. Secreted in milk.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P47710
PhosphoSite PhosphoSite-P47710
TrEMBL
UniProt Splice Variant
Entrez Gene 1446
UniGene Hs.3155
RefSeq NP_001881
HUGO HGNC:2445
OMIM 115450
CCDS CCDS47067
HPRD 00280
IMGT
EMBL AC108941 BC128227 BC128228 CH471057 DQ064604 U23157 X78416 X98084
GenPept AAA69477 AAI28228 AAI28229 AAY68392 CAA55185 CAA66708 EAX05599

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca