Version 5.4
Homo sapiens Protein: EIF3CL
Summary
InnateDB Protein IDBP-22323.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF3CL
Protein Name eukaryotic translation initiation factor 3, subunit C-like
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000370258
InnateDB Gene IDBG-22321 (EIF3CL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0031369 translation initiation factor binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
Cellular Component
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
Protein Structure and Domains
PDB ID
InterPro IPR000717 Proteasome component (PCI) domain
IPR008905 Eukaryotic translation initiation factor 3 subunit C, N-terminal domain
PFAM PF01399
PF05470
PRINTS
PIRSF
SMART SM00088
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt B5ME19
PhosphoSite PhosphoSite-B5ME19
TrEMBL H3BTY8
UniProt Splice Variant
Entrez Gene 728689
UniGene Hs.535464
RefSeq XP_005255592
HUGO HGNC:26347
OMIM
CCDS CCDS42136
HPRD
IMGT
EMBL AC138894 AC145285 CH878380
GenPept EAW50493 EAW50495

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca