Version 5.4
Homo sapiens Protein: UTP3
Summary
InnateDB Protein IDBP-22658.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UTP3
Protein Name UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000254803
InnateDB Gene IDBG-22656 (UTP3)
Protein Structure
UniProt Annotation
Function Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity). {ECO:0000250UniProtKB:Q12136, ECO:0000250UniProtKB:Q9JI13}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007420 brain development
GO:0016568 chromatin modification
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR007146 Sas10/Utp3/C1D
IPR018972 Sas10 C-terminal domain
PFAM PF04000
PF09368
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQZ2
PhosphoSite PhosphoSite-Q9NQZ2
TrEMBL
UniProt Splice Variant
Entrez Gene 57050
UniGene Hs.322901
RefSeq NP_065101
HUGO HGNC:24477
OMIM 611614
CCDS CCDS3546
HPRD 18016
IMGT
EMBL AF271212 AK026909 AL136590 BC004546 CR533544
GenPept AAF91408 AAH04546 BAB15588 CAB66525 CAG38575

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca