Version 5.4
Homo sapiens Protein: TOX
Summary
InnateDB Protein IDBP-22822.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOX
Protein Name thymocyte selection-associated high mobility group box
Synonyms TOX1;
Species Homo sapiens
Ensembl Protein ENSP00000354842
InnateDB Gene IDBG-22820 (TOX)
Protein Structure
UniProt Annotation
Function May play a role in regulating T-cell development. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00267}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94900
PhosphoSite PhosphoSite-O94900
TrEMBL B4DYA1
UniProt Splice Variant
Entrez Gene 9760
UniGene Hs.634856
RefSeq NP_055544
HUGO HGNC:18988
OMIM 606863
CCDS CCDS34897
HPRD 12113
IMGT
EMBL AB018351 AK302331 BC016665
GenPept AAH16665 BAA34528 BAG63663

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca