InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DIP2A

Summary

InnateDB Protein

IDBP-228596.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DIP2A

Protein Name

DIP2 disco-interacting protein 2 homolog A (Drosophila)

Synonyms

C21orf106; DIP2;

Species

Homo sapiens

Ensembl Protein

ENSP00000383133

InnateDB Gene

IDBG-6502 (DIP2A)

Protein Structure

UniProt Annotation

Function

May provide positional cues for axon pathfinding and patterning in the central nervous system.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Low expression in all tissues tested.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0008134	transcription factor binding

Biological Process

GO:0007275	multicellular organismal development
GO:0008152	metabolic process
GO:0010629	negative regulation of gene expression
GO:0042981	regulation of apoptotic process

Cellular Component

GO:0005634	nucleus
GO:0009986	cell surface

Protein Structure and Domains

PDB ID

InterPro

IPR000873 AMP-dependent synthetase/ligase
IPR010506 DMAP1-binding

PFAM

PF00501
PF06464

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q14689

PhosphoSite

PhosphoSite-Q14689

TrEMBL

Q9NSX6

UniProt Splice Variant

Entrez Gene

23181

UniGene

Hs.629325

RefSeq

NP_001139588

HUGO

HGNC:17217

OMIM

607711

CCDS

CCDS54490

HPRD

07611

IMGT

EMBL

AB273729 AF490768 AK056738 AK303351 AL137672 AP000337 AP000338 BC033718 BC038443 D80006

GenPept

AAH33718 AAH38443 AAM18046 BAA11501 BAB71268 BAF69070 BAG64412 CAB70868