InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RNASE10

Summary

InnateDB Protein

IDBP-2287.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RNASE10

Protein Name

ribonuclease, RNase A family, 10 (non-active)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000333358

InnateDB Gene

IDBG-2285 (RNASE10)

Protein Structure

UniProt Annotation

Function

Secreted proximal epididymal protein required for post- testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters

Biological Process

GO:0003382	epithelial cell morphogenesis
GO:0007338	single fertilization
GO:0008584	male gonad development
GO:0022409	positive regulation of cell-cell adhesion
GO:0034113	heterotypic cell-cell adhesion
GO:0072520	seminiferous tubule development
GO:0080154	regulation of fertilization
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
GO:1902093	positive regulation of sperm motility