InnateDB Protein
|
IDBP-231097.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
RUNX1
|
Protein Name
|
runt-related transcription factor 1
|
Synonyms
|
AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000382182
|
InnateDB Gene
|
IDBG-2825 (RUNX1)
|
Protein Structure
|
|
Function |
|
Subcellular Localization |
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 120 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated |
Total |
120
[view]
|
Protein-Protein |
101
[view]
|
Protein-DNA |
19
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
42 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0006355
|
regulation of transcription, DNA-templated
|
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR000040
Acute myeloid leukemia 1 protein (AML1)/Runt
IPR008967
p53-like transcription factor, DNA-binding
IPR013524
Runt domain
|
PFAM |
PF00853
|
PRINTS |
PR00967
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
A8MZI9
|
UniProt Splice Variant |
|
Entrez Gene |
861
|
UniGene |
Hs.717697
|
RefSeq |
|
HUGO |
HGNC:10471
|
OMIM |
151385
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
AF015262
AF015720
AF015721
AF015722
AF015723
AF015724
AF015725
AF015726
AF020800
AF020801
AF020802
AF020803
AF022141
AF022794
AF027207
AF051934
AF129107
AF129108
AP000330
AP000331
AP000332
AP000333
AP000334
AP000687
AP000688
|
GenPept |
|
|
|