Version 5.4
Homo sapiens Protein: SLC24A1
Summary
InnateDB Protein IDBP-231638.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC24A1
Protein Name solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
Synonyms CSNB1D; HsT17412; NCKX; NCKX1; RODX;
Species Homo sapiens
Ensembl Protein ENSP00000381991
InnateDB Gene IDBG-17643 (SLC24A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008273 calcium, potassium:sodium antiporter activity
GO:0015293 symporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0007601 visual perception
GO:0007603 phototransduction, visible light
GO:0009642 response to light intensity
GO:0016056 rhodopsin mediated signaling pathway
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019867 outer membrane
Protein Structure and Domains
PDB ID
InterPro IPR004481 Sodium/potassium/calcium exchanger
IPR004817 K+-dependent Na+/Ca+ exchanger
IPR004837 Sodium/calcium exchanger membrane region
PFAM PF01699
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60721
PhosphoSite PhosphoSite-O60721
TrEMBL
UniProt Splice Variant
Entrez Gene 9187
UniGene Hs.739856
RefSeq XP_005254838
HUGO HGNC:10975
OMIM 603617
CCDS CCDS73742
HPRD 04685
IMGT
EMBL AB014602 AC011939 AC027220 AF026132 AF062921 AF062922 BC117263 BC143375
GenPept AAB97832 AAC16732 AAC77912 AAI17264 AAI43376 BAA31677

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca