Version 5.4
Homo sapiens Protein: TMPRSS3
Summary
InnateDB Protein IDBP-233103.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMPRSS3
Protein Name transmembrane protease, serine 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000381442
InnateDB Gene IDBG-4346 (TMPRSS3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001190 SRCR domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel
IPR017448 SRCR-like domain
PFAM PF00530
PF00089
PF00057
PF09342
PRINTS PR00258
PR00722
PR00261
PIRSF
SMART SM00020
SM00192
SM00202
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B7WPR2
UniProt Splice Variant
Entrez Gene 64699
UniGene Hs.623456
RefSeq
HUGO HGNC:11877
OMIM 605511
CCDS
HPRD 05696
IMGT
EMBL AP001623
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca