Version 5.4
Homo sapiens Protein: ETNK1
Summary
InnateDB Protein IDBP-23441.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ETNK1
Protein Name ethanolamine kinase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000266517
InnateDB Gene IDBG-23439 (ETNK1)
Protein Structure
UniProt Annotation
Function Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity Expressed in kidney, liver, placenta, heart, leukocyte, ovary and testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004305 ethanolamine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0016310 phosphorylation
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002575 Aminoglycoside phosphotransferase
IPR004119 Protein of unknown function DUF227
IPR011009 Protein kinase-like domain
PFAM PF01636
PF02958
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HBU6
PhosphoSite PhosphoSite-Q9HBU6
TrEMBL
UniProt Splice Variant
Entrez Gene 55500
UniGene Hs.601593
RefSeq NP_061108
HUGO HGNC:24649
OMIM 609858
CCDS CCDS8698
HPRD 09934
IMGT
EMBL AC087241 AF207600 BC006111 BC066907 CH471094
GenPept AAF71220 AAH06111 AAH66907 EAW96479

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca