Version 5.4
Homo sapiens Protein: JARID2
Summary
InnateDB Protein IDBP-235655.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol JARID2
Protein Name jumonji, AT rich interactive domain 2
Synonyms JMJ;
Species Homo sapiens
Ensembl Protein ENSP00000380478
InnateDB Gene IDBG-62820 (JARID2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 32 [view]
Protein-Protein 28 [view]
Protein-DNA 3 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007417 central nervous system development
GO:0016568 chromatin modification
GO:0031061 negative regulation of histone methylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048863 stem cell differentiation
GO:0051574 positive regulation of histone H3-K9 methylation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0035097 histone methyltransferase complex
GO:0035098 ESC/E(Z) complex
Protein Structure and Domains
PDB ID
InterPro IPR001606 ARID/BRIGHT DNA-binding domain
IPR003347 JmjC domain
IPR003349 Transcription factor jumonji, JmjN
IPR004198 Zinc finger, C5HC2-type
PFAM PF01388
PF02373
PF08007
PF02375
PF02928
PRINTS
PIRSF
SMART SM00501
SM00558
SM00545
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92833
PhosphoSite PhosphoSite-Q92833
TrEMBL Q96PA1
UniProt Splice Variant
Entrez Gene 3720
UniGene Hs.732973
RefSeq NP_001253969
HUGO HGNC:6196
OMIM 601594
CCDS CCDS58996
HPRD 03355
IMGT
EMBL AF401209 AK292861 AK299349 AK303610 AL021938 AL136162 BC046184 BC046246 CH471087 U57592
GenPept AAC50822 AAH46184 AAH46246 AAL02168 BAF85550 BAH13011 BAH13996 CAI15719 CAI19873 EAW55357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca