InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IMP3

Summary

InnateDB Protein

IDBP-23577.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IMP3

Protein Name

IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000326981

InnateDB Gene

IDBG-23575 (IMP3)

Protein Structure

UniProt Annotation

Function

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. {ECO:0000269PubMed:12655004}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000269PubMed:12655004}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0019843	rRNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006364

rRNA processing

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0030529	ribonucleoprotein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001912 Ribosomal protein S4/S9, N-terminal
IPR002942 RNA-binding S4 domain

PFAM

PF00163
PF01479

PRINTS

PIRSF

SMART

SM00363

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NV31

PhosphoSite

PhosphoSite-Q9NV31

TrEMBL

Q96Q46

UniProt Splice Variant

Entrez Gene

55272

UniGene

RefSeq

HUGO

HGNC:14497

OMIM

612980

CCDS

CCDS10282

HPRD

12664

IMGT

EMBL

AB051628 AK001830 AK057531 AK223121 AL136913 AY050497 BC006487 BC011745 CH471136

GenPept

AAH06487 AAH11745 AAL06639 BAA91929 BAB54955 BAD96841 BAG51929 CAB66847 EAW99244