InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SNAP23

Summary

InnateDB Protein

IDBP-236013.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNAP23

Protein Name

synaptosomal-associated protein, 23kDa

Synonyms

HsT17016; SNAP-23; SNAP23A; SNAP23B;

Species

Homo sapiens

Ensembl Protein

ENSP00000380327

InnateDB Gene

IDBG-7946 (SNAP23)

Protein Structure

UniProt Annotation

Function

Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Subcellular Localization

Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Mainly localized to the plasma membrane.

Disease Associations

Tissue Specificity

Ubiquitous. Highest levels where found in placenta.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	69 [view]
Protein-Protein	68 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006892	post-Golgi vesicle-mediated transport
GO:0006903	vesicle targeting
GO:0015031	protein transport
GO:0045087	innate immune response (InnateDB)
GO:0061024	membrane organization
GO:0061025	membrane fusion

Cellular Component

GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0030054	cell junction
GO:0042581	specific granule
GO:0042582	azurophil granule
GO:0043005	neuron projection
GO:0045202	synapse
GO:0070062	extracellular vesicular exosome