Homo sapiens Protein: TULP3
Summary
InnateDB Protein IDBP-236053.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TULP3
Protein Name tubby like protein 3
Synonyms TUBL3;
Species Homo sapiens
Ensembl Protein ENSP00000380321
InnateDB Gene IDBG-12543 (TULP3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 3 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0019899 enzyme binding
GO:0032403 protein complex binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0001841 neural tube formation
GO:0001843 neural tube closure
GO:0006355 regulation of transcription, DNA-templated
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007275 multicellular organismal development
GO:0007420 brain development
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0008589 regulation of smoothened signaling pathway
GO:0009952 anterior/posterior pattern specification
GO:0021904 dorsal/ventral neural tube patterning
GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0021915 neural tube development
GO:0021953 central nervous system neuron differentiation
GO:0031076 embryonic camera-type eye development
GO:0042733 embryonic digit morphogenesis
GO:0045879 negative regulation of smoothened signaling pathway
GO:0048702 embryonic neurocranium morphogenesis
GO:0060173 limb development
GO:0060348 bone development
GO:0060434 bronchus morphogenesis
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:0061548 ganglion development
GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0005930 axoneme
GO:0030991 intraciliary transport particle A
GO:0072372 primary cilium
GO:0097546 ciliary base
Protein Structure and Domains
PDB ID
InterPro IPR000007 Tubby, C-terminal
IPR005398 Tubby, N-terminal
IPR025659 Tubby C-terminal-like domain
PFAM PF01167
PRINTS PR01573
PR01574
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75386
PhosphoSite PhosphoSite-O75386
TrEMBL F5H7B9
UniProt Splice Variant
Entrez Gene 7289
UniGene Hs.655333
RefSeq NP_001153880
HUGO HGNC:12425
OMIM 604730
CCDS CCDS53737
HPRD 05292
IMGT
EMBL AC005911 AF045583 AK024246 BC032587 CH471116
GenPept AAC95431 AAH32587 BAG51279 EAW88876 EAW88877 EAW88878