InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD72

Summary

InnateDB Protein

IDBP-236833.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD72

Protein Name

CD72 molecule

Synonyms

CD72b; LYB2;

Species

Homo sapiens

Ensembl Protein

ENSP00000379980

InnateDB Gene

IDBG-62668 (CD72)

Protein Structure

UniProt Annotation

Function

Plays a role in B-cell proliferation and differentiation.

Subcellular Localization

Membrane; Single-pass type II membrane protein.

Disease Associations

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

GO:0007155	cell adhesion
GO:0007165	signal transduction
GO:0007411	axon guidance

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001304 C-type lectin
IPR016187 C-type lectin fold

PFAM

PF00059

PRINTS

PIRSF

SMART

SM00034

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P21854

PhosphoSite

PhosphoSite-P21854

TrEMBL

Q5TLG3

UniProt Splice Variant

Entrez Gene

971

UniGene

RefSeq

HUGO

HGNC:1696

OMIM

107272

CCDS

CCDS6581

HPRD

00118

IMGT

EMBL

AB180952 AB180953 AB180954 AB180959 BC030227 CH471071 EF064751 M54992

GenPept

AAA36189 AAH30227 ABK41934 BAD72857 BAD72858 BAD72859 BAD72864 EAW58372 EAW58373