InnateDB Protein
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IDBP-237628.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MPV17L
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Protein Name
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MPV17 mitochondrial membrane protein-like
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000379669
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InnateDB Gene
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IDBG-16008 (MPV17L)
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Protein Structure
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Function |
Isoform 1 participates in reactive oxygen species metablism by up- or down-regulation of the genes of antioxidant enzymes. {ECO:0000269PubMed:16631601}.
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Subcellular Localization |
Isoform 1: Peroxisome membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Isoform 1 is detected in the kidney (at protein level). Isoform 1 and isoform 2 are expressed in the kidney, heart, liver, lung, pancreas and skeletal muscle. {ECO:0000269PubMed:16631601}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
GO:0010730
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negative regulation of hydrogen peroxide biosynthetic process
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GO:0072593
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reactive oxygen species metabolic process
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GO:1901029
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negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
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Cellular Component |
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PDB ID |
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InterPro |
IPR007248
Mpv17/PMP22
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PFAM |
PF04117
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q2QL34
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PhosphoSite |
PhosphoSite-Q2QL34
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
255027
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UniGene |
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RefSeq |
NP_001121895
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HUGO |
HGNC:26827
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OMIM |
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CCDS |
CCDS45421
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HPRD |
08803
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IMGT |
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EMBL |
AK096918
AK293380
BC061514
CH471226
DQ004255
DQ004256
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GenPept |
AAH61514
AAY58892
AAY58893
BAC04895
BAG56892
EAW53915
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