InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FXN

Summary

InnateDB Protein

IDBP-237666.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FXN

Protein Name

frataxin

Synonyms

CyaY; FA; FARR; FRDA; X25;

Species

Homo sapiens

Ensembl Protein

ENSP00000379652

InnateDB Gene

IDBG-69240 (FXN)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Biological Process

GO:0006783	heme biosynthetic process
GO:0006811	ion transport
GO:0006879	cellular iron ion homeostasis
GO:0008284	positive regulation of cell proliferation
GO:0010039	response to iron ion
GO:0010722	regulation of ferrochelatase activity
GO:0016226	iron-sulfur cluster assembly
GO:0016540	protein autoprocessing
GO:0018283	iron incorporation into metallo-sulfur cluster
GO:0030307	positive regulation of cell growth
GO:0043066	negative regulation of apoptotic process
GO:0044281	small molecule metabolic process
GO:0048554	positive regulation of metalloenzyme activity
GO:0051347	positive regulation of transferase activity
GO:0051349	positive regulation of lyase activity
GO:0051353	positive regulation of oxidoreductase activity
GO:0070301	cellular response to hydrogen peroxide
GO:0090201	negative regulation of release of cytochrome c from mitochondria