Version 5.4
Homo sapiens Protein: CSE1L
Summary
InnateDB Protein IDBP-238005.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSE1L
Protein Name CSE1 chromosome segregation 1-like (yeast)
Synonyms CAS; CSE1; XPO2;
Species Homo sapiens
Ensembl Protein ENSP00000379495
InnateDB Gene IDBG-80125 (CSE1L)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 91 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 91 [view]
Protein-Protein 87 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0008262 importin-alpha export receptor activity
GO:0008536 Ran GTPase binding
Biological Process
GO:0006611 protein export from nucleus
GO:0006886 intracellular protein transport
GO:0006915 apoptotic process
GO:0008283 cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001494 Importin-beta, N-terminal domain
IPR005043 CAS/CSE, C-terminal
IPR013713 Exportin/Importin, Cse1-like
IPR016024 Armadillo-type fold
PFAM PF03810
PF03378
PF08506
PRINTS
PIRSF
SMART SM00913
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P55060
PhosphoSite PhosphoSite-P55060
TrEMBL
UniProt Splice Variant
Entrez Gene 1434
UniGene Hs.90073
RefSeq NP_001243064
HUGO HGNC:2431
OMIM 601342
CCDS CCDS58773
HPRD 03217
IMGT
EMBL AF053640 AF053641 AF053642 AF053644 AF053645 AF053646 AF053647 AF053648 AF053649 AF053650 AF053651 AK312306 AL121903 AL133174 BC108309 BC109313 BC109314 CH471077 EF426455 U33286
GenPept AAC35007 AAC35008 AAC35009 AAC35297 AAC50367 AAI08310 AAI09314 AAI09315 ABO15009 BAG35231 CAI19615 CAI42818 EAW75676 EAW75677

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca