|
InnateDB Protein
|
IDBP-239940.5
|
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
|
Gene Symbol
|
ZNF365
|
|
Protein Name
|
zinc finger protein 365
|
|
Synonyms
|
Su48; UAN; ZNF365D;
|
|
Species
|
Homo sapiens
|
|
Ensembl Protein
|
ENSP00000378672
|
|
InnateDB Gene
|
IDBG-75545 (ZNF365)
|
|
Protein Structure
|
|
| Function |
May play a role in uric acid excretion.
|
| Subcellular Localization |
|
| Disease Associations |
Uric acid nephrolithiasis (UAN) [MIM:605990]: A form of nephrolithiasis, a common multifactorial disease characterized by stones formation in the kidney and urinary tract. Nephrolithiasis is due to supersaturation of the urine by stone-forming constituents, including calcium, oxalate and uric acid. Crystals or foreign bodies can act as nidi, upon which ions from the supersaturated urine form microscopic crystalline structures. Uric acid nephrolithiasis occurs when the urine becomes overly concentrated with uric acid and accounts for 20% of all stones. {ECO:0000269PubMed:12740763}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
|
| Tissue Specificity |
Isoform 4 is expressed in placenta, lung, kidney and pancreas. {ECO:0000269PubMed:12740763}.
|
| Comments |
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
4
[view]
|
| Protein-Protein |
3
[view]
|
| Protein-DNA |
1
[view]
|
| Protein-RNA |
0
|
| DNA-DNA |
0
|
| RNA-RNA |
0
|
| DNA-RNA |
0
|
|
|
|
| PDB ID |
|
| InterPro |
|
| PFAM |
|
| PRINTS |
|
| PIRSF |
|
| SMART |
|
| TIGRFAMs |
|
| Modification |
|
| SwissProt |
Q70YC4
|
| PhosphoSite |
PhosphoSite-
|
| TrEMBL |
|
| UniProt Splice Variant |
|
| Entrez Gene |
22891
|
| UniGene |
Hs.22653
|
| RefSeq |
NP_955524
|
| HUGO |
HGNC:18194
|
| OMIM |
607818
|
| CCDS |
CCDS7265
|
| HPRD |
06380
|
| IMGT |
|
| EMBL |
AC067751
AJ505150
|
| GenPept |
CAD43729
|
|
|
|
Version 5.4