InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPL8

Summary

InnateDB Protein

IDBP-240593.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL8

Protein Name

ribosomal protein L8

Synonyms

L8;

Species

Homo sapiens

Ensembl Protein

ENSP00000378378

InnateDB Gene

IDBG-41561 (RPL8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 124 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	124 [view]
Protein-Protein	122 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit

Protein Structure and Domains

PDB ID

InterPro

IPR002171 Ribosomal protein L2
IPR008991 Translation protein SH3-like domain
IPR012340 Nucleic acid-binding, OB-fold
IPR022666 Ribosomal Proteins L2, RNA binding domain
IPR022669 Ribosomal protein L2, C-terminal

PFAM

PF00181
PF03947

PRINTS

PIRSF

PIRSF002158

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P62917