Version 5.4
Homo sapiens Protein: TPPP3
Summary
InnateDB Protein IDBP-242575.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPPP3
Protein Name tubulin polymerization-promoting protein family member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377529
InnateDB Gene IDBG-36730 (TPPP3)
Protein Structure
UniProt Annotation
Function Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis. {ECO:0000269PubMed:17105200, ECO:0000269PubMed:19633818}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000305PubMed:17105200}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015631 tubulin binding
Biological Process
GO:0001578 microtubule bundle formation
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008907 P25-alpha
PFAM PF05517
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BW30
PhosphoSite PhosphoSite-Q9BW30
TrEMBL A0A024R702
UniProt Splice Variant
Entrez Gene 51673
UniGene
RefSeq NP_057048
HUGO HGNC:24162
OMIM
CCDS CCDS10835
HPRD 16710
IMGT
EMBL AF078846 AF132972 BC000691 CH471092
GenPept AAD27747 AAD44478 AAH00691 EAW83128 EAW83129 EAW83130 EAW83131

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca