Version 5.4
Homo sapiens Protein: SNX11
Summary
InnateDB Protein IDBP-243686.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX11
Protein Name sorting nexin 11
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000377059
InnateDB Gene IDBG-56631 (SNX11)
Protein Structure
UniProt Annotation
Function Phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. {ECO:0000269PubMed:23615901}.
Subcellular Localization Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Endosome {ECO:0000269PubMed:23615901}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0035091 phosphatidylinositol binding
GO:1901981 phosphatidylinositol phosphate binding
Biological Process
GO:0006886 intracellular protein transport
GO:0016050 vesicle organization
Cellular Component
GO:0005768 endosome
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001683 Phox homologous domain
PFAM PF00787
PRINTS
PIRSF
SMART SM00312
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y5W9
PhosphoSite PhosphoSite-Q9Y5W9
TrEMBL J3QRB9
UniProt Splice Variant
Entrez Gene 29916
UniGene Hs.710863
RefSeq NP_689450
HUGO HGNC:14975
OMIM 614906
CCDS CCDS11526
HPRD 15410
IMGT
EMBL AC006468 AF121861 AK023932 AK091852 AK296095 BC000768 BC103721 BT006723 CH471109
GenPept AAD27834 AAH00768 AAI03722 AAP35369 BAB14732 BAG52428 BAG58849 EAW94754

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca