InnateDB Protein
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IDBP-249081.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Wdr45
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Protein Name
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WD repeat domain 45
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Synonyms
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C79260; DXImx38e; JM5; Sfc19; Wdrx1; WIPI-4;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000111353
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InnateDB Gene
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IDBG-129365 (Wdr45)
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Protein Structure
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Function |
Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
7 [view]
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0032266
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phosphatidylinositol-3-phosphate binding
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GO:0080025
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phosphatidylinositol-3,5-bisphosphate binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1859606
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InterPro |
IPR001680
WD40 repeat
IPR017986
WD40-repeat-containing domain
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PFAM |
PF00400
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PRINTS |
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PIRSF |
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SMART |
SM00320
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TIGRFAMs |
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Modification |
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SwissProt |
Q91VM3
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PhosphoSite |
PhosphoSite-
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TrEMBL |
F7CAT9
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UniProt Splice Variant |
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Entrez Gene |
54636
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UniGene |
Mm.305725
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RefSeq |
NP_758960
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MGI ID |
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MGI Symbol |
Wdr45
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OMIM |
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CCDS |
CCDS29970
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HPRD |
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IMGT |
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EMBL |
AF229635
AK008427
AK145616
AL671995
BC011479
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GenPept |
AAF66949
AAH11479
BAB25662
BAE26542
CAM13587
CAM13588
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