Version 5.4
Homo sapiens Protein: SDAD1
Summary
InnateDB Protein IDBP-25031.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDAD1
Protein Name SDA1 domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000348596
InnateDB Gene IDBG-25029 (SDAD1)
Protein Structure
UniProt Annotation
Function Required for 60S pre-ribosomal subunits export to the cytoplasm. {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:11790298, ECO:0000269PubMed:14976432}.
Disease Associations
Tissue Specificity Highly expressed in testis, kidney, spleen, brain and fetal tissues. Also expressed at lower level in heart, lung, liver, small intestine, ovary, uterus, mammary gland and placenta. {ECO:0000269PubMed:14976432, ECO:0000269PubMed:15607425}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005488 binding
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0015031 protein transport
GO:0030036 actin cytoskeleton organization
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR007949 SDA1 domain
IPR012977 Uncharacterised domain NUC130/133, N-terminal
IPR016024 Armadillo-type fold
PFAM PF05285
PF08158
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NVU7
PhosphoSite PhosphoSite-Q9NVU7
TrEMBL
UniProt Splice Variant
Entrez Gene 55153
UniGene Hs.632604
RefSeq NP_060585
HUGO HGNC:25537
OMIM
CCDS CCDS3573
HPRD 10214
IMGT
EMBL AC110615 AC112719 AC115628 AK001360 AK022683 AK024031 BC054040 BC063797 BC107895 CR749574
GenPept AAH54040 AAH63797 AAI07896 BAA91648 BAB14177 BAB14790 CAH18368

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca