InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ocrl

Summary

InnateDB Protein

IDBP-250533.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Ocrl

Protein Name

oculocerebrorenal syndrome of Lowe

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000110665

InnateDB Gene

IDBG-142451 (Ocrl)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0030675	Rac GTPase activator activity
GO:0048365	Rac GTPase binding

Biological Process

GO:0001701	in utero embryonic development
GO:0007165	signal transduction
GO:0032314	regulation of Rac GTPase activity
GO:0032855	positive regulation of Rac GTPase activity
GO:0042384	cilium assembly
GO:0046856	phosphatidylinositol dephosphorylation

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005769	early endosome
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0005886	plasma membrane
GO:0030136	clathrin-coated vesicle

Protein Structure and Domains

PDB ID

MGI:109589

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR008936 Rho GTPase activation protein

PFAM

PF00620

PRINTS

PIRSF

SMART

SM00324

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q7TPR1

UniProt Splice Variant

Entrez Gene

320634

UniGene

Mm.472553

RefSeq

MGI ID

MGI Symbol

Ocrl

OMIM

CCDS

HPRD

IMGT

EMBL

AL714010 BC054840

GenPept

AAH54840