Version 5.4
Mus musculus Protein: Tmsb10
Summary
InnateDB Protein IDBP-252593.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmsb10
Protein Name thymosin, beta 10
Synonyms Ptmb10; Tb10;
Species Mus musculus
Ensembl Protein ENSMUSP00000109683
InnateDB Gene IDBG-252589 (Tmsb10)
Protein Structure
UniProt Annotation
Function Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0030036 actin cytoskeleton organization
GO:0042989 sequestering of actin monomers
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID MGI:109146
InterPro IPR001152 Thymosin beta-4
IPR016323 Thymosin beta-4, metazoa
PFAM PF01290
PRINTS
PIRSF PIRSF001828
SMART SM00152
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZWY8
PhosphoSite PhosphoSite-Q6ZWY8
TrEMBL A6H6H4
UniProt Splice Variant
Entrez Gene 19240
UniGene Mm.341466
RefSeq NP_001034481
MGI ID
MGI Symbol Tmsb10
OMIM
CCDS CCDS39519
HPRD
IMGT
EMBL AK003178 AK005512 AK008557 AK012361 AK019212 AK019232 AK131711 AK161987 BC145877 BC145879 CH466523
GenPept AAI45878 AAI45880 BAB22622 BAB24091 BAB25742 BAB28189 BAB31603 BAB31614 BAE20774 BAE36668 EDK98997

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca