InnateDB Protein
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IDBP-252815.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Spag16
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Protein Name
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sperm associated antigen 16
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Synonyms
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4921511D23Rik; 4930524F24Rik; 4930585K05Rik; AV261009; Pf20; Wdr29;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000109573
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InnateDB Gene
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IDBG-164299 (Spag16)
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Protein Structure
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Function |
Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia. {ECO:0000269PubMed:19305393}.
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Subcellular Localization |
Cytoplasm. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium axoneme. Note=Detected on the sperm flagellum. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules.
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Disease Associations |
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Tissue Specificity |
Expressed in testis. {ECO:0000269PubMed:12391165}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1913972
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K450
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
66722
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UniGene |
Mm.440554
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RefSeq |
NP_001258462
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MGI ID |
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MGI Symbol |
Spag16
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OMIM |
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CCDS |
CCDS69901
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HPRD |
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IMGT |
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EMBL |
AF490391
AK014865
AK015884
AK016618
AK083083
BC120668
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GenPept |
AAI20669
AAM97148
BAB29591
BAB30016
BAB30341
BAC38755
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