InnateDB Protein
|
IDBP-253040.5
|
Last Modified
|
2012-02-14 [Report errors or provide feedback]
|
Gene Symbol
|
Adrbk1
|
Protein Name
|
adrenergic receptor kinase, beta 1
|
Synonyms
|
Adrbk-1; Bark-1; beta ARK; betaARK1; GRK2;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000109468
|
InnateDB Gene
|
IDBG-129419 (Adrbk1)
|
Protein Structure
|
|
Function |
|
Subcellular Localization |
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Experimentally validated |
Total |
14
[view]
|
Protein-Protein |
14
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
38 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0002026
|
regulation of the force of heart contraction
|
GO:0002029
|
desensitization of G-protein coupled receptor protein signaling pathway
|
GO:0006468
|
protein phosphorylation
|
GO:0007186
|
G-protein coupled receptor signaling pathway
|
GO:0007507
|
heart development
|
GO:0018105
|
peptidyl-serine phosphorylation
|
GO:0018107
|
peptidyl-threonine phosphorylation
|
GO:0038032
|
termination of G-protein coupled receptor signaling pathway
|
|
Cellular Component |
|
PDB ID |
MGI:87940
|
InterPro |
IPR000342
Regulator of G protein signalling domain
IPR016137
Regulator of G protein signalling superfamily
|
PFAM |
PF00615
|
PRINTS |
PR01301
|
PIRSF |
|
SMART |
SM00315
|
TIGRFAMs |
|
Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
E9Q419
|
UniProt Splice Variant |
|
Entrez Gene |
110355
|
UniGene |
Mm.254144
|
RefSeq |
|
MGI ID |
|
MGI Symbol |
Adrbk1
|
OMIM |
|
CCDS |
|
HPRD |
|
IMGT |
|
EMBL |
AC140073
|
GenPept |
|
|
|