Version 5.4
Mus musculus Protein: Zer1
Summary
InnateDB Protein IDBP-253374.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zer1
Protein Name zer-1 homolog (C. elegans)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000109307
InnateDB Gene IDBG-155445 (Zer1)
Protein Structure
UniProt Annotation
Function Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0051438 regulation of ubiquitin-protein ligase activity
Cellular Component
GO:0031462 Cul2-RING ubiquitin ligase complex
Protein Structure and Domains
PDB ID MGI:2442511
InterPro IPR000225 Armadillo
IPR016024 Armadillo-type fold
PFAM PF00514
PRINTS
PIRSF
SMART SM00185
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80ZJ6
PhosphoSite PhosphoSite-Q80ZJ6
TrEMBL Q3U297
UniProt Splice Variant
Entrez Gene 227693
UniGene Mm.488942
RefSeq NP_001277432
MGI ID
MGI Symbol Zer1
OMIM
CCDS CCDS71017
HPRD
IMGT
EMBL AK029290 AK032318 AK048853 AK087046 AK155401 BC048924 BC057021 BX005298 CH466542
GenPept AAH48924 AAH57021 BAC26374 BAC27811 BAC33474 BAC39788 BAE33245 CAM18958 EDL08437

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca