InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Swi5

Summary

InnateDB Protein

IDBP-253964.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Swi5

Protein Name

SWI5 recombination repair homolog (yeast)

Synonyms

1500019F05Rik; 2900010J23Rik; AI046671;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000109027

InnateDB Gene

IDBG-159259 (Swi5)

Protein Structure

UniProt Annotation

Function

Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. {ECO:0000269PubMed:20976249}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:20976249}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0071479	cellular response to ionizing radiation

Cellular Component

GO:0005634	nucleus
GO:0032798	Swi5-Sfr1 complex

Protein Structure and Domains

PDB ID

MGI:1920181

InterPro

IPR010760 DNA repair protein, Swi5

PFAM

PF07061

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K3D3

PhosphoSite

PhosphoSite-ENSMUSP00000109027

TrEMBL

E3WH32

UniProt Splice Variant

Entrez Gene

72931

UniGene

Mm.27344

RefSeq

NP_001277481

MGI ID

MGI Symbol

Swi5

OMIM

CCDS

CCDS71026

HPRD

IMGT

EMBL

AB597964 AB597965 AK013517 AK166608 AL808027 BC021748 CH466542

GenPept

AAH21748 BAC25409 BAE38890 BAJ25750 BAJ25751 CAM15841 CAM15843 EDL08533 EDL08534