InnateDB Protein
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IDBP-254473.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Rab3il1
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Protein Name
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RAB3A interacting protein (rabin3)-like 1
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Synonyms
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1200014K04Rik; AI115013; C76746; Rab3ail1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000108786
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InnateDB Gene
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IDBG-142981 (Rab3il1)
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Protein Structure
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Function |
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activates RAB8A and RAB8B (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0017112
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Rab guanyl-nucleotide exchange factor activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1922010
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InterPro |
IPR009449
GDPGTP exchange factor Sec2p
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PFAM |
PF06428
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8VDV3
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PhosphoSite |
PhosphoSite-Q8VDV3
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TrEMBL |
D3YZN2
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UniProt Splice Variant |
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Entrez Gene |
74760
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UniGene |
Mm.488681
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RefSeq |
NP_653121
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MGI ID |
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MGI Symbol |
Rab3il1
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OMIM |
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CCDS |
CCDS29569
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HPRD |
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IMGT |
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EMBL |
AC134437
AK132764
AK161298
BC020147
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GenPept |
AAH20147
BAE21345
BAE36305
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