InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il1rapl2

Summary

InnateDB Protein

IDBP-254682.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il1rapl2

Protein Name

interleukin 1 receptor accessory protein-like 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108686

InnateDB Gene

IDBG-173736 (Il1rapl2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Detected in fetal brain after day 12.5, in particular in parts of the diencephalon and in the basal plate of the spinal cord. In postnatal brain detected in cerebral cortex, olfactory bulb, in the CA1 region of the hippocampus and in Purkinje cells of the Xth cerebellar lobule. {ECO:0000269PubMed:11587848}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004910	interleukin-1, Type II, blocking receptor activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0019221	cytokine-mediated signaling pathway

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1913106

InterPro

IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR004077 Interleukin-1 receptor type II
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set

PFAM

PF01582
PF13676
PF07679

PRINTS

PR01539

PIRSF

SMART

SM00255
SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt