Version 5.4
| Mus musculus Protein: Rabgap1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-254951.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Rabgap1 | ||||||||
| Protein Name | RAB GTPase activating protein 1 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000108542 | ||||||||
| InnateDB Gene | IDBG-165901 (Rabgap1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition (By similarity). {ECO:0000250UniProtKB:Q9Y3P9}. | ||||||||
| Subcellular Localization | Cytoplasm, cytosol {ECO:0000250UniProtKB:Q9Y3P9}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250UniProtKB:Q9Y3P9}. Note=Predominantly cytosolic but also associated with the centrosome. {ECO:0000250UniProtKB:Q9Y3P9}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2385139 | ||||||||
| InterPro |
IPR000195
Rab-GTPase-TBC domain IPR006020 PTB/PI domain IPR022164 Kinesin-like |
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| PFAM |
PF00566
PF00640 PF14719 PF12473 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00164
SM00462 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | A2AWA9 | ||||||||
| PhosphoSite | PhosphoSite-A2AWA9 | ||||||||
| TrEMBL | B2RRC5 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 227800 | ||||||||
| UniGene | Mm.438200 | ||||||||
| RefSeq | XP_006498057 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Rabgap1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS16002 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK031315 AK044346 AK051644 AK220489 AL953890 BC026862 BC031714 BC138337 CH466542 | ||||||||
| GenPept | AAH26862 AAH31714 AAI38338 BAC27344 BAC31880 BAC34703 BAD90509 CAM20742 CAM20743 EDL08711 | ||||||||