InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Steap3

Summary

InnateDB Protein

IDBP-255586.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Steap3

Protein Name

STEAP family member 3

Synonyms

1010001D01Rik; pHyde; Tsap6;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000108262

InnateDB Gene

IDBG-188010 (Steap3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000293	ferric-chelate reductase activity
GO:0008823	cupric reductase activity
GO:0052851	ferric-chelate reductase (NADPH) activity

Biological Process

GO:0006826	iron ion transport
GO:0009306	protein secretion
GO:0015677	copper ion import
GO:0055114	oxidation-reduction process
GO:0097461	ferric iron import into cell
GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1990182	exosomal secretion

Cellular Component

GO:0005768	endosome
GO:0005771	multivesicular body
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

MGI:1915678

InterPro

IPR013130 Ferric reductase transmembrane component-like domain
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal

PFAM

PF01794
PF03807

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9QN92

UniProt Splice Variant

Entrez Gene

68428

UniGene

Mm.181033

RefSeq

MGI ID

MGI Symbol

Steap3

OMIM

CCDS

HPRD

IMGT

EMBL

AC084310 AC139867

GenPept