InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ntf3

Summary

InnateDB Protein

IDBP-256423.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ntf3

Protein Name

neurotrophin 3

Synonyms

AI316846; AI835689; Nt3; Ntf-3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000107863

InnateDB Gene

IDBG-190188 (Ntf3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005166	neurotrophin p75 receptor binding
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0042056	chemoattractant activity
GO:0048406	nerve growth factor binding

Biological Process

GO:0000187	activation of MAPK activity
GO:0002092	positive regulation of receptor internalization
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007274	neuromuscular synaptic transmission
GO:0007399	nervous system development
GO:0007403	glial cell fate determination
GO:0007411	axon guidance
GO:0007420	brain development
GO:0007422	peripheral nervous system development
GO:0008284	positive regulation of cell proliferation
GO:0008544	epidermis development
GO:0021675	nerve development
GO:0030335	positive regulation of cell migration
GO:0032148	activation of protein kinase B activity
GO:0032856	activation of Ras GTPase activity
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0042490	mechanoreceptor differentiation
GO:0042552	myelination
GO:0043523	regulation of neuron apoptotic process
GO:0043524	negative regulation of neuron apoptotic process
GO:0045687	positive regulation of glial cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048484	enteric nervous system development
GO:0048666	neuron development
GO:0048699	generation of neurons
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
GO:0050804	regulation of synaptic transmission
GO:0050918	positive chemotaxis
GO:0050930	induction of positive chemotaxis
GO:0051145	smooth muscle cell differentiation
GO:2000251	positive regulation of actin cytoskeleton reorganization