InnateDB Protein
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IDBP-257174.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Arhgdib
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Protein Name
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Rho, GDP dissociation inhibitor (GDI) beta
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Synonyms
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D4; Gdid4; Ly-GDI;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000107522
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InnateDB Gene
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IDBG-195168 (Arhgdib)
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Protein Structure
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|
Function |
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
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Subcellular Localization |
Cytoplasm.
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Disease Associations |
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Tissue Specificity |
Preferentially expressed in hematopoietic cells.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
|
Protein-Protein |
7
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
14 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0005094
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Rho GDP-dissociation inhibitor activity
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GO:0005096
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GTPase activator activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:101940
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InterPro |
IPR000406
RHO protein GDP dissociation inhibitor
IPR014756
Immunoglobulin E-set
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PFAM |
PF02115
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PRINTS |
PR00492
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PIRSF |
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SMART |
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TIGRFAMs |
|
Modification |
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SwissProt |
Q61599
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PhosphoSite |
PhosphoSite-Q61599
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TrEMBL |
D3YWL7
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UniProt Splice Variant |
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Entrez Gene |
11857
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UniGene |
Mm.486330
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RefSeq |
XP_006505465
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MGI ID |
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MGI Symbol |
Arhgdib
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OMIM |
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CCDS |
CCDS20661
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HPRD |
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IMGT |
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EMBL |
AC125341
AK002516
AK169733
BC031763
L07918
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GenPept |
AAA61613
AAH31763
BAB22155
BAE41335
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