InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Igsf9

Summary

InnateDB Protein

IDBP-258558.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Igsf9

Protein Name

immunoglobulin superfamily, member 9

Synonyms

644ETD8; Dasm1; Kiaa1355-hp; mKIAA1355; Ncaml; NRT1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106866

InnateDB Gene

IDBG-205479 (Igsf9)

Protein Structure

UniProt Annotation

Function

Functions in dendrite outgrowth and synapse maturation. {ECO:0000269PubMed:15340156, ECO:0000269PubMed:15340157}.

Subcellular Localization

Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Enriched at the excitatory synapses in mature neurons. {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in both cell bodies and dendrites of cortical and hippocampal neurons and also cerebellar Purkinje cells (at protein level). {ECO:0000269PubMed:15340157}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0016358

dendrite development

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030425	dendrite
GO:0045202	synapse

Protein Structure and Domains

PDB ID

MGI:2135283

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q05BQ1