InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cnpy4

Summary

InnateDB Protein

IDBP-259198.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cnpy4

Protein Name

canopy 4 homolog (zebrafish)

Synonyms

2610019P18Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106559

InnateDB Gene

IDBG-205986 (Cnpy4)

Protein Structure

UniProt Annotation

Function

Plays a role in the regulation of the cell surface expression of TLR4. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Highly expressed in lung, spleen, thymus, and uterus. Moderately expressed in kidney, stomach and placenta. Weakly expressed in brain, heart, liver, small intestine, skeletal muscle and testis. {ECO:0000269PubMed:16338228}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding

Biological Process

GO:0032880

regulation of protein localization

Cellular Component

GO:0005575	cellular_component
GO:0005576	extracellular region

Protein Structure and Domains

PDB ID

MGI:1913705

InterPro

IPR021852 Domain of unknown function DUF3456

PFAM

PF11938

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BQ47

PhosphoSite

PhosphoSite-Q8BQ47

TrEMBL

UniProt Splice Variant

Entrez Gene

66455

UniGene

Mm.24592

RefSeq

NP_848727

MGI ID

MGI Symbol

Cnpy4

OMIM

CCDS

CCDS39341

HPRD

IMGT

EMBL

AK011474 AK012968 AK033219 AK051562 BC086647 BC094672

GenPept

AAH86647 AAH94672 BAC25336 BAC25383 BAC28201 BAC34675