Version 5.4
Mus musculus Protein: Wdr76
Summary
InnateDB Protein IDBP-259913.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr76
Protein Name WD repeat domain 76
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000106232
InnateDB Gene IDBG-202462 (Wdr76)
Protein Structure
UniProt Annotation
Function Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. {ECO:0000269PubMed:23434322}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1926186
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6PWY4
PhosphoSite PhosphoSite-A6PWY4
TrEMBL
UniProt Splice Variant
Entrez Gene 241627
UniGene Mm.293284
RefSeq NP_084510
MGI ID
MGI Symbol Wdr76
OMIM
CCDS CCDS38218
HPRD
IMGT
EMBL AK020004 AL928678 BC094676 BC117822
GenPept AAH94676 AAI17823 BAB31961 CAM19245 CAM19246 CAO78067

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca