InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc12a1

Summary

InnateDB Protein

IDBP-260153.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc12a1

Protein Name

solute carrier family 12, member 1

Synonyms

AI788571; D630042G03Rik; mBSC1; Nkcc2; urehr3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106121

InnateDB Gene

IDBG-203493 (Slc12a1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015377	cation:chloride symporter activity

Biological Process

GO:0001822	kidney development
GO:0006810	transport
GO:0006811	ion transport
GO:0007588	excretion
GO:0048878	chemical homeostasis
GO:0055085	transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane

Protein Structure and Domains

PDB ID

MGI:103150

InterPro

IPR002443 Na/K/Cl co-transporter
IPR002445 Na/K/Cl co-transporter 2
IPR004841 Amino acid permease/ SLC12A domain
IPR004842 Na/K/Cl co-transporter superfamily
IPR013612 Amino acid permease, N-terminal

PFAM

PF00324
PF08403

PRINTS

PR01207
PR01209

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite