InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Snx25

Summary

InnateDB Protein

IDBP-260398.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Snx25

Protein Name

sorting nexin 25

Synonyms

AI661919; Gm1699; Gm173; Sbbi31;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000106007

InnateDB Gene

IDBG-153599 (Snx25)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0034713	type I transforming growth factor beta receptor binding
GO:0035091	phosphatidylinositol binding

Biological Process

GO:0015031	protein transport
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032801	receptor catabolic process
GO:0038032	termination of G-protein coupled receptor signaling pathway
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation

Cellular Component

GO:0005768	endosome
GO:0010008	endosome membrane

Protein Structure and Domains

PDB ID

MGI:2142610

InterPro

IPR000342 Regulator of G protein signalling domain
IPR001683 Phox homologous domain
IPR003114 Phox-associated domain
IPR013937 Sorting nexin, C-terminal
IPR013996 PX-associated, sorting nexin 13
IPR016137 Regulator of G protein signalling superfamily

PFAM

PF00615
PF00787
PF02194
PF08628

PRINTS

PR01301

PIRSF

SMART

SM00312
SM00313
SM00315

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt